Anencephaly is a type of neural tube defect. Neural tube defects, spina bifida (open spine) and anencephaly (open skull) are seen in one to two per 1, live births. During pregnancy, the human brain and spine begin as a flat plate of cells, which rolls into a tube, called the neural tube. Did your baby have further birth defects? Other observations (placenta previa, homebirth, emergency c-section, breech position) Do you have a family history of neural tube defects (did a sibling, nephew, niece, uncle, aunt, cousin, yourself or another of your children have anencephaly, spina bifida or another neural tube defect)? Jun 23, · Born With Anencephaly Baby Angela Was LifeNews has frequently profiled Baby the couple found out their daughter had fatal birth defects.